Now You Know Medical Textile Wound Care (Part-1)
Tuesday 22 January 2019
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MEDI-TEX WOUND CARE (PART-1)
Medical textile is an emerging area with numerous uses, Medical textile products are produced from high performance textile materials that are manufactured primarily for their functional and performance properties rather than their aesthetic or decorative properties. Studies have carried out in the present work to impart the properties of WOUND HEALING and antibacterial finishes in medical textiles producing a “MEDICATED HERBAL BANDAGE”. An eco-friendly natural finish has been prepared from the medicinal herb –extracts to achieve the properties of wound healing and antimicrobial finish. Ethanol extract of the herbs were directly applied on % on cotton gauze by pad- dry- cure method. Padding was carried out in padding mangle at pressure of 3psi to get a pickup of 100% on weight of fabric. Drying and curing was carried out at 80 degree Celsius for 3 mints respectively. Thus the medicated herbal bandage has been prepared. The treated and untreated samples are tested using test methods like SEM, FTIR and WOUND HEALING and ANTIBACTERIAL TESTS and ABSORBENCY TESTS.
Keywords: Mimosa Pudica, Cotton Gauze, Wound Healing, Antibacterial.
1. INTRODUCTION
MIMOSA PUDICA also called as sensitive plant, sleepy plant and the touch me not is a creeping annual or perennial herb often grown, for its curiosity value, the compound leaves fold inward and droop when touched or shake, to protect them from predators, reopening minutes later. It grows mostly in shady areas, under trees or shrubs. The stem is erect in young plants, but becomes creeping or trailing with age. It can hang very low and become floppy. The stem is slender, branching and sparsely to densely prickly, growing to a length of 1.5m. The leaves of the mimosa pudica are compound leaves. The leaves are bipinnately compound, with one or two pinnae pairs, and 10-26 leaflets per pinna. The petioles are also prickly. The fruit consists of clusters of 2-8 pods from 1-2cm long each, these being prickly on the margins. The pods break into 2-5 segments and contain pale brown seeds some 2.5mm. The flowers are pollinated by wind and insects. Mimosa pudica is well known for its rapid movement. The leaves also close under various other stimuli, such as touching, warming, blowing, or shaking. These type of movements have been termed as seismonastic movement. The movement occurs when specific regions of cells lose turgor pressure, which is the force applied onto the cell wall by water within the cell vacuoles and other cell contents. When the plant is disturbed, specific regions on the stem are stimulated to release chemicals including potassium ions which force out of the cell vacuoles and the water diffuses out of the cells, producing a loss of cell pressure and cell collapse, this differential turgidity between different regions of cells result in the closing of the leaflets and the collapse of the leaf petiole.
PURPOSE OF CHOOSING MIMOSA PUDICA
An injury to living tissue caused by a cut, blow, or other impact, typically one in which the skin is cut or broken. Wound is breakdown in the protective function of the skin; the loss of continuity of epithelium, with or without loss of underlying connective tissue (i.e. muscle, bone, nerves) following injury to the skin is called wound.
CLASSIFICATION OF WOUND
The first principle of wound care is the removal of nonviable tissue, including necrotic (dead) tissue, slough, foreign debris, and residual material from dressings. The second principle of wound care is to provide a moist environment. This has been shown to promote re epithelialization and healing. Preventing further injury is the third principle of wound care. This involves elimination or reduction of the condition that allowed the wound to develop.
Dressings are important to maintain sterility and absorb blood and serum. Moisture improves the rate of epithelialization. The goal is a state of optimal hydration of the wound margins – not too wet or too dry. Sutured or stapled lacerations should be covered with a non-adherent dressing for the first 1 to 2 days to also allow sufficient epithelialization to prevent gross contamination.
2. MATERIAL AND METHODS
Plant collection and authentication:
Mimosa Pudica leaves were collected from the fields and the leaves of the mimosa pudica are compound leaves. The leaves are bipinnately compound, with one or two pinnae pair, and 10-26 leaflets per pinna. Mimosa pudica is well known for its rapid movement. The leaves also under various other stimuli, such as touching, warming, blowing or shaking. All the five parts of plant leaves, flowers, stems, roots and fruits are used as medicines in the traditional healthcare systems. It has ability to promote health cell growth. Leaves have been popular use for treating various ailments since long. Mostly, leaves of mimosa pudica are showed maximum pharmacological activity as ant diabetic, antitoxin, antioxidant, and antibacterial and wound healing activity.
Cotton GAUZE
Gauze is the bleached woven cloth used for dressing, bandages and absorbent sponges. It is a thin translucent fabric with loose open weave. Weave structure is arranged in such a manner that the pair of weft yarns cross before and after each warp yarn keeping the weft yarn firmly in place which gives stability to the fabric.
METHODOLOGY
Preparation of Herbal Extraction
The leaves of Mimosa Pudica were collected from the lands and it has been dried under shadow of sunlight to remove the moisture content present in the leaves. The dried leaves were grinded into powder for further process. The powdered leaves was mixed with ethanol in soxhlet apparatus in the ratio of 1:10 and made to boil it for 1 hour at 50 degree Celsius for about one cycle. After the completion of one full cycle, the extract was separated to get the residue at the bottom. The extract was filtered and thus the herbal extract is produced.
Padding Process
The extract of mimosa pudica was followed for fabric padding. The cotton gauze has been taken to padding mangle maintaining the room temperature and normal pH. The padding mangle used is two bowl padding mangle with each bowl of 1kg. The cotton gauze were impregnated in the herbal extract for about half hour at room temperature and it has been squeezed using pair of bowls with the pressure of 0.75 psi so the padding was done uniformly in the full width of the fabric and excess amount of liquor have been squeezed out. Thus the herbal finished fabric is taken for drying and the finished fabric is named as “Medicated Herbal Bandage”.
Medicated Herbal Bandage
Ethanol extracts of herbs were directly applied on cotton gauze by padding method to promote wound healing in short time and to reduce the risk of bacterial infection. Since mimosa pudica plant has abundantly available in many of the countries, the scope of implementation and commercialization of herbal extract to impart finishes in textile is will be high and raw material is 100% natural resources, it is ecofriendly having economic, social and environmental benefits. Thus the medicated herbal bandage is prepared and various performance test have been carried out. The test follows are FTIR, SEM, absorbency test, antibacterial, phytochemical analysis and wound healing activity.
Keywords: Mimosa Pudica, Cotton Gauze, Wound Healing, Antibacterial.
1. INTRODUCTION
MIMOSA PUDICA also called as sensitive plant, sleepy plant and the touch me not is a creeping annual or perennial herb often grown, for its curiosity value, the compound leaves fold inward and droop when touched or shake, to protect them from predators, reopening minutes later. It grows mostly in shady areas, under trees or shrubs. The stem is erect in young plants, but becomes creeping or trailing with age. It can hang very low and become floppy. The stem is slender, branching and sparsely to densely prickly, growing to a length of 1.5m. The leaves of the mimosa pudica are compound leaves. The leaves are bipinnately compound, with one or two pinnae pairs, and 10-26 leaflets per pinna. The petioles are also prickly. The fruit consists of clusters of 2-8 pods from 1-2cm long each, these being prickly on the margins. The pods break into 2-5 segments and contain pale brown seeds some 2.5mm. The flowers are pollinated by wind and insects. Mimosa pudica is well known for its rapid movement. The leaves also close under various other stimuli, such as touching, warming, blowing, or shaking. These type of movements have been termed as seismonastic movement. The movement occurs when specific regions of cells lose turgor pressure, which is the force applied onto the cell wall by water within the cell vacuoles and other cell contents. When the plant is disturbed, specific regions on the stem are stimulated to release chemicals including potassium ions which force out of the cell vacuoles and the water diffuses out of the cells, producing a loss of cell pressure and cell collapse, this differential turgidity between different regions of cells result in the closing of the leaflets and the collapse of the leaf petiole.
PURPOSE OF CHOOSING MIMOSA PUDICA
- Mimosa Pudica promotes wound healing in the shortest time possible, with minimum pain.
- It is a good product which is very best for human health.
- The leaves of Mimosa pudica have very good anti-bacterial property.
- To promote wound healing.
- To reduce the pain of the wound.
- To immobilize the injured part of body.
- To protect the wound and surrounding tissues.
- To keep the wound clean and prevent contamination by foreign bodies.
- To reduce the risk of bacterial infection.
An injury to living tissue caused by a cut, blow, or other impact, typically one in which the skin is cut or broken. Wound is breakdown in the protective function of the skin; the loss of continuity of epithelium, with or without loss of underlying connective tissue (i.e. muscle, bone, nerves) following injury to the skin is called wound.
CLASSIFICATION OF WOUND
- Acute wound
- Chronic wound
- Non-penetrating wounds: These are usually the result of blunt trauma or friction with other surfaces; the wound does not break through the skin.
- Penetrating wounds: These results from trauma that breaks through the full thickness of skin; reaching down to the underlying tissue and organs.
The first principle of wound care is the removal of nonviable tissue, including necrotic (dead) tissue, slough, foreign debris, and residual material from dressings. The second principle of wound care is to provide a moist environment. This has been shown to promote re epithelialization and healing. Preventing further injury is the third principle of wound care. This involves elimination or reduction of the condition that allowed the wound to develop.
- Prevention of wound complications and promotion of wound healing.
- Wound healing is the restoration of continuity of cells.
- Wound healing involves the synthesis of several types of tissue and scar formation.
Dressings are important to maintain sterility and absorb blood and serum. Moisture improves the rate of epithelialization. The goal is a state of optimal hydration of the wound margins – not too wet or too dry. Sutured or stapled lacerations should be covered with a non-adherent dressing for the first 1 to 2 days to also allow sufficient epithelialization to prevent gross contamination.
2. MATERIAL AND METHODS
Plant collection and authentication:
Mimosa Pudica leaves were collected from the fields and the leaves of the mimosa pudica are compound leaves. The leaves are bipinnately compound, with one or two pinnae pair, and 10-26 leaflets per pinna. Mimosa pudica is well known for its rapid movement. The leaves also under various other stimuli, such as touching, warming, blowing or shaking. All the five parts of plant leaves, flowers, stems, roots and fruits are used as medicines in the traditional healthcare systems. It has ability to promote health cell growth. Leaves have been popular use for treating various ailments since long. Mostly, leaves of mimosa pudica are showed maximum pharmacological activity as ant diabetic, antitoxin, antioxidant, and antibacterial and wound healing activity.
 |
| Fig 1: Mimosa Pudica Plant leaves |
Gauze is the bleached woven cloth used for dressing, bandages and absorbent sponges. It is a thin translucent fabric with loose open weave. Weave structure is arranged in such a manner that the pair of weft yarns cross before and after each warp yarn keeping the weft yarn firmly in place which gives stability to the fabric.
 |
| Fig 2: Cotton Gauze |
The leaves of Mimosa Pudica were collected from the lands and it has been dried under shadow of sunlight to remove the moisture content present in the leaves. The dried leaves were grinded into powder for further process. The powdered leaves was mixed with ethanol in soxhlet apparatus in the ratio of 1:10 and made to boil it for 1 hour at 50 degree Celsius for about one cycle. After the completion of one full cycle, the extract was separated to get the residue at the bottom. The extract was filtered and thus the herbal extract is produced.
 |
| Fig 3: Extraction in soxhlet |
The extract of mimosa pudica was followed for fabric padding. The cotton gauze has been taken to padding mangle maintaining the room temperature and normal pH. The padding mangle used is two bowl padding mangle with each bowl of 1kg. The cotton gauze were impregnated in the herbal extract for about half hour at room temperature and it has been squeezed using pair of bowls with the pressure of 0.75 psi so the padding was done uniformly in the full width of the fabric and excess amount of liquor have been squeezed out. Thus the herbal finished fabric is taken for drying and the finished fabric is named as “Medicated Herbal Bandage”.
Medicated Herbal Bandage
Ethanol extracts of herbs were directly applied on cotton gauze by padding method to promote wound healing in short time and to reduce the risk of bacterial infection. Since mimosa pudica plant has abundantly available in many of the countries, the scope of implementation and commercialization of herbal extract to impart finishes in textile is will be high and raw material is 100% natural resources, it is ecofriendly having economic, social and environmental benefits. Thus the medicated herbal bandage is prepared and various performance test have been carried out. The test follows are FTIR, SEM, absorbency test, antibacterial, phytochemical analysis and wound healing activity.
 | |
| Fig 4: Medicated Herbal Bandage |